Syndyphalin-33, a synthetic tripeptide alkylamide with prolonged analgesic activity

Analgesic activity of new synthetic thiazolidine-4-ones derivatives.

Ten new synthetic thiazolidine-4-ones derivatives (5 chlorothiazolidine-4-ones, 3 methoxythiazolidine-4-ones and 2 hydoxythiazolidine-4-ones) having different substituents at R1, R2 and R3 were evaluated for their analgesic activity using different animal models and their structure activity relationship was also elucidated. Chlorothiazolidine-4-ones and methoxythiazolidine-4-ones exhibited anal...

Effects of Weaning and Syndyphalin-33 on Appetite Regulators in Swine

Analgesic, Anticonvulsant and Antiparkinsonian Activities of Some Synthesized 2,6-bis(Tetracarboxamide)-pyridine and Macrocyclic Tripeptide Derivatives

A series of synthesized 2,6-bis(tetracarboxamide)-pyridine and macrocyclic tripeptide derivatives 1-6 were previously prepared and screened as antimicrobial, anti-inflammatory and anticancer agents. The compounds for evaluation of analgesic, anticonvulsant and antiparkinsonian activities were used. Analgesic activities of selected compounds determined by hot plate assay, all tested compounds sh...

Evaluation of Analgesic activity of Ficus palmata

Background: Ficus palmata (FI) is an important and widely used medicinal plant. It is principally used as an item of diet in the treatment of constipation and diseases of the lungs and bladder. The sap is used in the treatment of warts. Ficus palmata plant is used in various disease e.g. gastrointestinal, hypoglycemic, antitumor, anti-ulcer, anti-diabetic, lipid lowering and antifungal activiti...

Prolonged corticotrophic action of a synthetic substituted 1-18 ACTH.

The adrenocorticotrophic effects of a synthetic corticotrophin analogue, alpha(1-18) ACTH with D-serine(1), lysine(17), and lysine amide(18) substitutions has been studied. It is effective after both intramuscular and subcutaneous administration and compared with tetracosactrin depot (Synacthen depot, Cortrosyn depot) it has a similarly prolonged time course of action-about 24 hours after 0.5 m...